Changes that occur in one person’s cancer may not occur in others who have the same type of cancer.
The same cancer-causing changes may be found in different types of cancer.
To be eligible for precision medicine, your tumor must be tested for genetic change that can be targeted by a treatment currently available in the market or in Clinical Trials.
To figure out which genetic changes are in your cancer, you may need to have a biopsy.
A biopsy is a procedure in which your doctor removes a sample of the cancer.
Your sample will be sent to the Star Biosciences Lab, where a machine called a DNA sequencer looks for genetic changes that may be causing the cancer to grow.
The process of looking for genetic changes in cancer may be called DNA sequencing, genomic testing, molecular profiling, or tumor profiling.
Immuno-Oncology (I-O) is the investigation of innovative approaches that aim to harness the body’s natural immune response to fight cancer.
Immuno-Oncology testing helps determine which patients are good candidates for immunotherapy. Star Bioscience Laboratories is a leader in precision diagnostics and is at the forefront of immunotherapy testing.
Tumor Mutation Burden (TMB): This genomic biomarker is designed to predict response to checkpoint inhibitor immunotherapies targeting the PD-1 and PD-L1 proteins. Studies in lung, melanoma and bladder cancers showed that objective response to checkpoint immunotherapy was predicted by the presence of high TMB.
Microsatellite Instability (MSI) and Mismatch Repair (MMR): KEYTRUDA® was approved by the FDA for the treatment of certain patients with metastatic solid tumors that have been identified as being MSI-high or mismatch repair deficient (dMMR)1. OPDIVO® is FDA-approved for certain colorectal cancer patients with MSI-high or dMMR2.
PD-L1: This immunohistochemical assay detects the level and expression sites of PD-L1 protein. As a companion or complementary diagnostic for certain tumors and indications, it helps identify patients for treatments including KEYTRUDA, OPDIVO, TECENTRIQ® and IMFINZI™.
Its a "Blood Test". It helps your doctor identify whether your treatment is working and pinpoints the status of your disease progression. Tests are highly specific for Lung, Breast, Colon and Prostate Cancers. Test results are delivered within 5 days.
Testing using liquid biopsies is more sensitive than other diagnostic testing methods like bone marrow taps, which are invasive and painful for patients.
Targeted therapy is a newer type of cancer treatment that uses drugs or other substances to more precisely identify and attack cancer cells. Targeted therapy is a growing part of the treatment for many types of cancer.
Multi-Gene testing helps your doctor identify drugs that work against the "Genetic Defect" causing your Cancer. These tests are performed on "All Cancer Types" and help Personalize your Treatment.
Cancer Specific tests:
Star Biosciences brings breadth and depth of service to support oncologists in making diagnoses, assessing prognoses, and discovering opportunities for targeted therapy in their patients with solid tumors.